Neurology

 

Healthcare Professional Tools

  • KetoCal Once Per Day

    Learn more about the benefits of recommending KetoCal 4:1 once per day to your patients, including nutritional reassurance, everyday convenience and increased fat intake for MAD patients!

  • KetoCal Household Measurements

    KetoCal 3:1 powder and KetoCal 4:1 powder household measurements included. To ensure accuracy, we recommend always using a gram scale to measure KetoCal. However, we recognize that patients following a Modified Atkins Diet may use household measurements instead, so we provide them to healthcare professionals when requested.

  • KetoCal 4:1 Powder - June 2016 Product Update FAQs

    Answers to clinician's frequently asked questions regarding upgrades to KetoCal 4:1 powder reformulation. June 2016

  • My Keto Planner

    *NEW* We are excited to introduce My Keto Planner™: a new diet management tool, recipe sharing database, and social network, specifically designed for the Ketogenic Diet Community! Healthcare professionals and caregivers create their own accounts that can be linked together (Note: caregivers have limited use of the program until their account is linked with a healthcare provider). Register for free at MyKetoPlanner.com. Healthcare professional user guide and a My Keto Planner Q&A available to help getting started.  *Please note: My Keto Planner is currently available in the U.S. only. For information on availability in your country, please contact your local Nutricia office.

  • KetoCal DRI Calculator

    This file can be used by Healthcare Professionals to compare macro and micro nutrients provided by the desired amount of KetoCal** to the DRIs (as of 2010). **Includes the full range of KetoCal family of products (KetoCal 3:1 Powder, KetoCal 4:1 Powder, and KetoCal 4:1 LQ Unflavored & Vanilla). Use the tabs along the bottom of the page to select the product you are using. Enter the number of calories as directed at the top of the page and press enter to automatically calculate the nutrients provided by that amount, and the corresponding percentage of DRI values met for each age group.

  • Consent Form (US)

    In order for caregiver's to purchase or receive samples of KetoCal directly from Nutricia, healthcare providers must provide a consent form.  Completed consents forms can by faxed to 301-795-2292 or emailed to customerservice@nutricia.com. Please note: consent forms must be updated annually.

Flowcharts/Guidelines

  • The Clinician's Product Selection Guide

    This guide illustrates the most appropriate and convenient choice of ketogenic formula for various types of ketogenic diet. It is a tool that may be used as a decision making guide for clinicians. The flowchart poses guiding questions and considerations to ensure patients nutrition needs are being met. It includes a list of the KetoCal family of products.

Reference Library

  • Clinical Studies Using KetoCal

    References for Clinical Studies Using KetoCal.

    • Kossoff EH et al. Prospective study of the Modified Atkins Diet in combination with a ketogenic liquid supplement during the initial month. J Child Neurol 2011;26(2):147-51 PubMed
    • Coppola G, et al. Ketogenic diet for the treatment of catastrophic epileptic encephalopathies in childhood. Eur J Paediatr Neurol. 2010 May;14(3):229-34. PubMed
    • Wusthoff CJ, et al. The ketogenic diet in treatment of two adults with prolonged nonconvulsive status epilepticus. Epilepsia. 2010 Jun;51(6):1083-5. PubMed
    • Rubenstein JE. Use of the ketogenic diet in neonates and infants. Epilepsia. 2008 Nov;49 Suppl 8:30-2. PubMed
  • The Ketogenic Diet for Children with Intractable Epilepsy

    Clinical References for The Ketogenic Diet for Children with Intractable Epilepsy.

    • Aguirre Castaneda RL, et al. Successful treatment of type 1 diabetes and seizures with combined ketogenic diet and insulin. Pediatrics. 2012 Feb;129(2):e511-4. PubMed
    • Cusmai R, et al. Ketogenic diet in early myoclonic encephalopathy due to non ketotic hyperglycinemia. Eur J Paediatr Neurol. 2012 Jan 17. [Epub ahead of print] PubMed
    • Groomes LB, et al. Do patients with absence epilepsy respond to ketogenic diets? J Child Neurol. 2011 Feb;26(2):160-5. PubMed
    • Dressler A, et al. Long-term outcome and tolerability of the ketogenic diet in drug-resistant childhood epilepsy--the Austrian experience. Seizure. 2010 Sep;19(7):404-8. PubMed
    • Patel A, et al. Long-term outcomes of children treated with the ketogenic diet in the past. Epilepsia. 2010 Jul;51(7):1277-82. PubMed
    • Kossoff EH. The ketogenic diet: an appropriate first-line therapy? Expert Rev Neurother. 2010 Jun;10(6):843-5. PubMed
    • Coppola G, et al. Ketogenic diet for the treatment of catastrophic epileptic encephalopathies in childhood. Eur J Paediatr Neurol. 2010 May;14(3):229-34. PubMed
    • Kossoff EH, et al. Ketogenic Diets: An Update for Child Neurologists. J Child Neurol. 2009 Aug;24(8):979-88. PubMed
    • Neal EG, et al. A randomized trial of classical and medium-chain triglyceride ketogenic diets in the treatment of childhood epilepsy. Epilepsia. 2009;50(5):1109–17. PubMed
    • Rubenstein JE. Use of the ketogenic diet in neonates and infants. Epilepsia. 2008 Nov;49 Suppl 8:30-2. PubMed
    • Kossoff EH, et al. Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group. Epilepsia. 2009 Feb;50(2):304-17. PubMed
    • Freeman JM, et al. The ketogenic diet: one decade later. Pediatrics. 2007 Mar;119(3):535-43. Abstract
    • Bergqvist AG, et al. Vitamin D status in children with intractable epilepsy, and impact of the ketogenic diet. Epilepsia. 2007 Jan;48(1):66-71. PubMed
    • Hartman AL, et al. Clinical aspects of the ketogenic diet. Epilepsia. 2007 Jan;48(1):31-42. Abstract
    • Bough KJ, et al. Anticonvulsant mechanisms of the ketogenic diet. Epilepsia. 2007 Jan;48(1):43-58. PubMed
    • Groesbeck DK, et al. Long-term use of the ketogenic diet in the treatment of epilepsy. Dev Med Child Neurol. 2006 Dec;48(12):978-81. PubMed
    • Henderson CB, et al. Efficacy of the ketogenic diet as a treatment option for epilepsy: meta-analysis. J Child Neurol. 2006 Mar;21(3):193-8. PubMed
    • Bergqvist AG, et al. Fasting versus gradual initiation of the ketogenic diet: a prospective, randomized clinical trial of efficacy. Epilepsia. 2005 Nov;46(11):1810-9. PubMed
    • Rubenstein JE, et al. Experience in the use of the ketogenic diet as early therapy. J Child Neurol. 2005 Jan;20(1):31-4. PubMed
    • Pfeifer HH, et al. Low-glycemic-index treatment: a liberalized ketogenic diet for treatment of intractable epilepsy. Neurology. 2005 Dec 13;65(11):1810-2. PubMed
    • Kossoff EH, et al. Benefits of an all-liquid ketogenic diet. Epilepsia. 2004 Sep;45(9):1163. PubMed
    • Mandel A, et al. Medical costs are reduced when children with intractable epilepsy are successfully treated with the ketogenic diet. J Am Diet Assoc. 2002 Mar;102(3):396-8. PubMed
    • Hemingway C, et al. The ketogenic diet: a 3- to 6-year follow-up of 150 children enrolled prospectively. Pediatrics. 2001 Oct;108(4):898-905. PubMed
    • Freeman JM, et al. The efficacy of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children. Pediatrics. 1998 Dec;102(6):1358-63. PubMed
  • The Modified Atkins Diet for Children with Intractable Epilepsy

    Clinical References for The Modified Atkins Diet for Children with Intractable Epilepsy.

    • Sharma S, et al. Use of the modified Atkins diet in infantile spasms refractory to first-line treatment. Seizure. 2012 Jan;21(1):45-8. PubMed
    • Kim YM, et al. Various indications for a modified Atkins diet in intractable childhood epilepsy. Brain Dev. 2011 Oct 14. PubMed
    • Kossoff EH, et al. Prospective study of the Modified Atkins Diet in combination with a ketogenic liquid supplement during the initial month. J Child Neurol 2011;26(2):147-51. PubMed
    • Ito Y, et al. A modified Atkins diet is promising as a treatment for glucose transporter type 1 deficiency syndrome. Dev Med Child Neurol. 2011 Jul;53(7):658-63. PubMed
    • Miranda MJ, et al. Danish study of a Modified Atkins diet for medically intractable epilepsy in children: Can we achieve the same results as with the classical ketogenic diet? Seizure. 2011;20:151-155. PubMed
    • Kumada T, et al. Modified Atkins Diet for the Treatment of Nonconvulsive Status Epilepticus in Children. J Child Neurol. 2010;25(4):485-489. PubMed
    • Kossoff EH, at al. A pilot study of the modified Atkins diet for Sturge-Weber syndrome. Epilepsy Res. 2010 Dec;92(2-3):240-3. PubMed
    • Barzegar M, et al. A Modified Atkins Diet for Intractable Epilepsy. Iran J Child Neurology. 2010;4(3):15-20. Abstract
    • Tonekaboni SH, et al. Efficacy of the Atkins diet as therapy for intractable epilepsy in children. Archives of Iranian Medicine. 2010;13(6):492-7. PubMed
    • Porta N, et al. Comparison of seizure reduction and serum fatty acid levels after receiving the ketogenic and modified Atkins diet. Seizure. 2009;18(5):359–364. PubMed
    • Kang HC, et al. Use of a modified Atkins diet in intractable childhood epilepsy. Epilepsia. 2007;48(1):182–6. PubMed
    • Kossoff EH, et al. A randomized, crossover comparison of daily carbohydrate limits using the modified Atkins diet. Epilepsy Behav. 2007 May;10(3):432-6. PubMed
    • Kossoff EH, et al. A modified Atkins diet is effective for the treatment of intractable pediatric epilepsy. Epilepsia. 2006;47(2):421-4. PubMed
  • Dietary Therapies for Adults with Epilepsy

    Clinical References for Dietary Therapies for Adults with Epilepsy

    • Wusthoff CJ, et al. The ketogenic diet in treatment of two adults with prolonged nonconvulsive status epilepticus. Epilepsia. 2010 Jun;51(6):1083-5. PubMed
  • Infantile Spasms

    Clinical References for Infantile Spasms.

    • Sharma S, et al Use of the modified Atkins diet in infantile spasms refractory to first-line treatment. Seizure. 2012 Jan;21(1):45-8. PubMed
    • Numis AL, et al. The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms. Epilepsy Res. 2011 Jun 21. PubMed
    • Hong AM, et al. Infantile spasms treated with the ketogenic diet: prospective single-center experience in 104 consecutive infants. Epilepsia. 2010 Aug;51(8):1403-7. PubMed
    • Kossoff EH, et al. A case-control evaluation of the ketogenic diet versus ACTH for new-onset infantile spasms. Epilepsia. 2008 Sep;49(9):1504-9. PubMed
    • Eun SH, et al. Ketogenic diet for treatment of infantile spasms. Brain Dev. 2006 Oct;28(9):566-71. PubMed
    • Kossoff EH, et al. Efficacy of the ketogenic diet for infantile spasms. Pediatrics. 2002 May;109(5):780-3. PubMed
  • Glut1 Deficiency Syndrome

    Clinical References for Glut1 Deficiency Syndrome.

    • Ito Y, et al. A modified Atkins diet is promising as a treatment for glucose transporter type 1 deficiency syndrome. Dev Med Child Neurol. 2011 Jul;53(7):658-63. PubMed
    • Klepper J. Glucose transporter deficiency syndrome (GLUT1DS) and the ketogenic diet. Epilepsia. 2008 Nov;49 Suppl 8:46-9. PubMed
    • Cornejo VE, et al. Glucose transponer type 1 deficiency síndrome (GLUT-1 SD) treated with ketogenic diet. Report of one case. Rev Med Chil. 2007 May;135(5):631-5. PubMed
  • Dravet Syndrome

    Clinical References for Dravet Syndrome

    • Nabbout R, et al. Ketogenic diet also benefits Dravet syndrome patients receiving stiripentol: A prospective pilot study. Epilepsia. 2011 Jul;52(7):e54-7. PubMed
    • Veggiotti P, et al. The ketogenic diet for Dravet syndrome and other epileptic encephalopathies: an Italian consensus. Epilepsia. 2011 Apr;52 Suppl 2:83-9. PubMed
    • Caraballo RH. Nonpharmacologic treatments of Dravet syndrome: focus on the ketogenic diet. Epilepsia. 2011 Apr;52 Suppl 2:79-82. PubMed
    • Caraballo RH, et al. Ketogenic diet in patients with Dravet syndrome. Epilepsia. 2005 Sep;46(9):1539-44. PubMed
  • Myoclonic Astatic Epilepsy (also known as Doose Syndrome)

    Clinical References for Myoclonic Astatic Epilepsy (also known as Doose Syndrome).

    • Mulligan JE, et al. Myoclonic astatic epilepsy and the role of the ketogenic diet. Med Health R I. 2011 May;94(5):127-30. PubMed
    • Kossoff EH, et al. Will seizure control improve by switching from the modified Atkins diet to the traditional ketogenic diet? Epilepsia. 2010 Dec;51(12):2496-9. PubMed
    • Caraballo RH, et al. Ketogenic diet in patients with myoclonic-astatic epilepsy. Epileptic Disord. 2006 Jun;8(2):151-5. PubMed
  • Sturge-Weber Syndrome

    Clinical References for Sturge-Weber Syndrome.

    • Kossoff EH, et al. A pilot study of the modified Atkins diet for Sturge-Weber syndrome. Epilepsy Res. 2010 Dec;92(2-3):240-3. PubMed
  • Tuberous Sclerosis

    Clinical References for Tuberous Sclerosis.

    • Coppola G, et al.The effects of the ketogenic diet in refractory partial seizures with reference to tuberous sclerosis. Eur J Paediatr Neurol. 2006 May;10(3):148-51. Epub 2006 Apr 24. PubMed
    • Kossoff EH, et al. Tuberous sclerosis complex and the ketogenic diet. Epilepsia. 2005 Oct;46(10):1684-6. PubMed
  • Pyruvate Dehydrogenase Deficiency

    Clinical References for Pyruvate Dehydrogenase Deficiency.

    • El-Gharbawy AH, et al. Follow-up of a child with pyruvate dehydrogenase deficiency on a less restrictive ketogenic diet. Mol Genet Metab. 2011 Feb;102(2):214-5. PubMed
    • Wexler ID, et al. Outcome of pyruvate dehydrogenase deficiency treated with ketogenic diets. Studies in patients with identical mutations. Neurology. 1997 Dec;49(6):1655-61. PubMed
    • Wijburg FA, et al. Leigh syndrome associated with a deficiency of the pyruvate dehydrogenase complex: results of treatment with a ketogenic diet. Neuropediatrics. 1992 Jun;23(3):147-52. PubMed
    • Falk RE, et al. Ketonic diet in the management of pyruvate dehydrogenase deficiency. Pediatrics. 1976 Nov;58(5):713-21. PubMed
  • Refractory Status Epilepticus

    Clinical References for Refractory Status Epilepticus.

    • Cervenka MC, et al. The ketogenic diet for medically and surgically refractory status epilepticus in the neurocritical care unit. Neurocrit Care. 2011 Dec;15(3):519-24. PubMed
    • Nam SH, et al. The role of ketogenic diet in the treatment of refractory status epilepticus. Epilepsia. 2011 Nov;52(11):e181-4. PubMed
    • Wusthoff CJ, et al. The ketogenic diet in treatment of two adults with prolonged nonconvulsive status epilepticus. Epilepsia. 2010 Jun;51(6):1083-5. PubMed
    • Kumada T, et al. Modified Atkins diet for the treatment of nonconvulsive status epilepticus in children. J Child Neurol. 2010 Apr;25(4):485-9. PubMed
  • Generalized vs. Focal Epilepsy

    Clinical References for Generalized vs. Focal Epilepsy.

    • Kayyali H, et al. A. The Ketogenic Diet Efficacy in Generalized vs Focal Epilepsy (abstract). In: American Epilepsy Society’s Annual Meeting; 2 Dec 2011-6 Dec-2011; Baltimore, MD. Abstract 2.293. Abstract
  • Non Ketotic Hyperglycinemia

    Clinical References for Non Ketotic Hyperglycinemia.

    • Cusmai R, et al. Ketogenic diet in early myoclonic encephalopathy due to non ketotic hyperglycinemia. Eur J Paediatr Neurol. 2012 Jan 17. [Epub ahead of print] PubMed
  • CDKL5 Mutation

    Clinical References for CDKL5 Mutation.

    • Moseley BD, et al. Historic, Clinical, and Prognostic Features of Epileptic Encephalopathies Caused by CDKL5 Mutations. Pediatr Neurol. 2012 Feb;46(2):101-5. PubMed

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