GI/Allergy

 

Healthcare Professional Tools

  • Duocal, Information for Healthcare Professionals

    This resource is for healthcare professionals recommending Duocal, a flavorless powder with a unique dual-energy source of carbohydrate & fat. The document includes a description of Duocal; nutrient information; a guide for recommending Duocal (based on a daily calorie goal); information on how to prepare, store & mix in foods; and lastly, how to order.

  • Neocate DRI Calculator and Mixing Tool

    Updated as of April 2020: Includes 2019 DRI updates for Sodium and Potassium and all updates to Neocate formulas in Canada.

    • Neocate DRI Calculator: This tab can be used by Healthcare Professionals to compare nutrients provided by a chosen amount of any Neocate product to the Dietary Reference Intakes (DRIs) for a chosen gender and age range.
    • Neocate Mixing Tool: This tab helps the Healthcare Professional to calculate mixing instructions for preparing Neocate powders at a desired concentration and volume for individual patients. This tool can also be used by Healthcare Professionals to calculate a recipe that yields an approximate gram weight of Neocate powder using household measures, and to determine the number of cans needed per month.

  • 7 Red Flag Indicators for Using an Amino Acid-Based Formula to Manage Cow Milk Allergy

    Your next patient with food allergies could present with a combination of these 7 red flag indicators:

    • Download Quick Reference Guide
    • Meyer R, Groetch M, Venter C. When Should Infants with Cow's Milk Protein Allergy Use an Amino Acid Formula? A Practical Guide. J Allergy Clin Immunol Pract. 2018;6:383-99. Abstract
  • Neocate Pocket Guide – US

    Updated as of February 2019: Includes entire upgraded US Neocate Junior range. Provides clinical information on all the Neocate products, including select nutrition information, ingredient sources, and mixing instructions at various concentrations for each formula.

  • Mixing Charts for Neocate Infant Formulas

    These resources have been developed for use by Healthcare Professionals. They contain recipes at various concentrations, up to 30 kcal/fl oz, either for mixing Neocate infant formulas with water or for combining breast milk with Neocate infant formula powders.

  • Neocate Family Comparison Chart

    Updated December 2018. A nutrient comparison chart for all Neocate products in the US. Also includes indications, main features and reimbursement codes.

  • Monogen Dilution Chart

    This resource has been developed for use by Healthcare Professionals. It includes recipes for mixing Monogen at multiple dilutions (from 20 to 30 calories per fluid ounce), as well as household measures.

  • Monitoring Micronutrients

    This guidance is intended to provide an update on monitoring micronutrients for healthcare professionals.

  • Neocate Junior and Splash Dilution Charts

    Updated December 2019: These resources are for healthcare professionals. They include recipes for mixing Neocate Junior and/or Neocate Splash at various concentrations. Please Note: charts for Neocate Junior powders differ slightly due to different energy densities, scoop fill, and displacement. Canadian healthcare professionals: Please contact us at 866.636.2283 to request appropriate charts for Neocate products in the Canadian market.

  • Letters of Medical Necessity

    We created sample letters of medical necessity to help patients request insurance coverage for Neocate. You can complete the missing information and individualize the letters to suit your patient's situation and needs. Simply follow the appropriate links below to access Word files. Please note: our Nutricia Product Coverage Navigator team is available to help your patients to obtain coverage for our medical foods. This includes assistance with drafting letters of medical necessity, obtaining prior authorization for our products, correcting billing errors, appealing denied claims and much more. If your patients need personalized assistance with Neocate coverage call 1-800-365-7354 or email NutriciaNavigator@nutricia.com

  • Duocal Tools

    This tool helps to determine an amount of Duocal to add to any enteral formula. It offers both an interactive calculator and two printable concentration charts to help in adding calories to enteral formulas with Duocal. It also offers an interactive calculator that can generate a combination of US household measures that provide an approximate gram weight of Duocal when a scale is not available and the provided scoop is not convenient.

Flowcharts/Guidelines

  • Short Bowel Syndrome Management Flow Chart

    This flow chart illustrates different options for the dietary management of Short Bowel Syndrome and where amino acid-based formulas fit in. It is an evidence based tool that may be used as a decision making guide for clinicians. The flow chart includes a list of the Neocate® family of products.

  • Cow Milk Allergy/Multiple Food Allergies (CMA/MFA) Dietary Management Flow Chart

    This flow chart is an evidence-based tool that may be used as a decision-making guide for clinicians. It illustrates options for the dietary management of CMA/MFA, and where elemental nutrition (Neocate®) fits in. The flow chart poses guiding questions and considerations to ensure patients’ nutrition needs are being met. It includes a list of the Neocate family of products.

  • Eosinophilic Esophagitis (EoE) Management Flow Chart

    This flow chart is an evidence-based tool that may be used as a decision-making guide for clinicians. It illustrates possible signs and symptoms that can help identify EoE patients, options for the dietary management of EoE, and where elemental nutrition (Neocate®) fits in. The flow chart poses guiding questions and considerations to ensure patients’ nutrition needs are being met. It includes a list of the Neocate family of products.

Reference Library

  • Cow Milk Allergy (CMA) & Gut Microbiota

    Clinical References for Neocate related to Cow Milk Allergy (CMA) and Gut Microbiota

    • Candy DCA, Van Ampting MTJ, Oude Nijhuis MM, et al. A synbiotic-containing amino-acid-based formula improves gut microbiota in non-IgE-mediated allergic infants. Pediatr Res. 2018;83:677-86. Full Text
    • Fox AT, Wopereis H, Van Ampting MTJ, et al. A specific synbiotic-containing amino acid-based formula in dietary management of cow's milk allergy: a randomized controlled trial. Clin Transl Allergy. 2019;9:5. Full Text
    • Wopereis H, van Ampting MTJ, Cetinyurek-Yavuz A, et al. A specific synbiotic-containing amino acid-based formula restores gut microbiota in non-IgE mediated cow's milk allergic infants: a randomized controlled trial. Clin Transl Allergy. 2019;9:27. Full Text
  • Cow Milk Allergy (CMA)

    Clinical References for Neocate related to Cow Milk Allergy (CMA)

    • Colson D, Kalach N, Soulaines P, et al. Anthropomorphic variations according to clinical pattern in cow's milk allergic children. 2014 AAAAI Annual Meeting. San Diego, CA. J Allergy Clin Immunol. 2014;133(2):AB65(231). Abstract
    • Miller J. “Like taking away his lifeline”: recognizing and addressing the role of food as a sensory regulation strategy in children with autism. ICAN: Infant Child & Adolescent Nutrition. 2013;5(5):274-82. Abstract
    • Colson D, Michaud B, Soulaines P, et al. Long term nutritional outcome of children fed by an amino-acid formula. 2013 AAAAI Annual Meeting. February 22-26, 2013; San Antonio, TX. J Allergy Clin Immunol. 2013;131(2):AB98(355). Abstract
    • Munoz Urribarri A, Delgado Godos A, Castillo Duran R, et al. [Case report: allergy to cow's milk protein]. Rev Gastroenterol Peru. 2011;31(2):183-7. PubMed
    • Epifanio M, Spolidoro JV, Soder RB, et al. Gray-scale and color Doppler ultrasound findings in children with cow's milk allergy. AJR Am J Roentgenol. 2011;196(6):W817-22. Full Text
    • Srinivasan P, Brandler M, D'Souza A, et al. J Perinatol. 2010;30(6):431-3. PubMed
    • Koksal B, Ozbek O, Hosnut F, et al. Food protein induced proctocolitis in five infants. XXIX EAACI Congress. June 2010; London, UK. Allergy. 2010;65(420(1117). Abstract
    • Dupont C, Soulaines P, Lapillonne A, et al. J Pediatr Gastroenterol Nutr. 2010;50(4):463-4. PubMed
    • Becker PJ. ICAN: Infant Child & Adolescent Nutrition. 2009;1(4):214-9. Abstract
    • Maloney J, Nowak-Wegrzyn A. Educational clinical case series for pediatric allergy and immunology: allergic proctocolitis, food protein-induced enterocolitis syndrome and allergic eosinophilic gastroenteritis with protein-losing gastroenteropathy as manifestations of non-IgE-mediated cow's milk allergy. Pediatr Allergy Immunol. 2007;18(4):360-7. PubMed
    • Hill DJ, Murch SH, Rafferty K, et al. The efficacy of amino acid-based formulas in relieving the symptoms of cow's milk allergy: a systematic review. Clin Exp Allergy. 2007;37(6):808-22. PubMed
    • Faber MR, Rieu P, Semmekrot BA, et al. Acta Paediatr. 2005;94(10):1514-5. PubMed
    • Hernandez-Trujillo VP, Nguyen WT, Belleau JT, et al. Cow's milk allergy in a patient with hyper-IgE syndrome. Ann Allergy Asthma Immunol. 2004;92(4):469-74. PubMed
    • Hernandez-Trujillo VP, Belleau JT, Nguyen WT, et al. Beneficial effect of an amino-acid based formula for neonatal eosinophilic folliculitis associated with hyper-IgE syndrome and cow's milk allergy. J Allergy Clin Immunol. 2003;111(2):S228-. Abstract
    • Kanny G, Moneret-Vautrin DA, Flabbee J, et al. [Use of an amino acid-based formula in the treatment of cow's milk protein allergy and multiple food allergy syndrome]. Allerg Immunol (Paris). 2002;34(3):82-4. PubMed
    • Dupont C, de Boissieu D. [Treatment of severe allergy to cow's milk proteins by Neocate®]. Allerg Immunol (Paris). 2002;34(3):85-90. PubMed
    • de Boissieu D, Dupont C. Allergy to extensively hydrolyzed cow's milk proteins in infants: safety and duration of amino acid-based formula. J Pediatr. 2002;141(2):271-3. PubMed
    • Niggemann B, Binder C, Dupont C, et al. Prospective, controlled, multi-center study on the effect of an amino-acid-based formula in infants with cow's milk allergy/intolerance and atopic dermatitis. Pediatr Allergy Immunol. 2001;12(2):78-82. PubMed
    • Moneret-Vautrin DA, Hatahet R, Kanny G. [Milk protein hydrolysates: hypoallergenic formulas and extensively hydrolyzed formulas: allergologic basis for their use in prevention and treatment of cow's milk allergy]. Arch Pediatr. 2001;8(12):1348-57. PubMed
    • D'Netto MA, Herson VC, Hussain N, et al. J Pediatr. 2000;137(4):480-6. PubMed
    • de Boissieu D, Dupont C. Time course of allergy to extensively hydrolyzed cow's milk proteins in infants. J Pediatr. 2000;136(1):119-20. PubMed
    • Sotto D, Tounian P, Baudon JJ, et al. [Allergy to cow's milk protein hydrolysates: apropos of 8 cases]. Arch Pediatr. 1999;6(12):1279-85. PubMed
    • Dupont C, Niggemann B, Binder C, et al. Early introduction of an amino acid-based vs protein hydrolysate formula in children with cow milk allergy: a randomised multicentre trial. ESPGHAN 32nd Annual Meeting. June 2-5, 1999; Warsaw, Poland. J Pediatr Gastroenterol Nutr. 1999;28(5):589(17). Abstract
    • Ammar F, de Boissieu D, Dupont C. [Allergy to protein hydrolysates. Report of 30 cases]. Arch Pediatr. 1999;6(8):837-43. PubMed
    • Isolauri E, Sutas Y, Salo MK, et al. Elimination diet in cow's milk allergy: risk for impaired growth in young children. J Pediatr. 1998;132(6):1004-9. PubMed
    • Lake AM. Beyond hydrolysates: use of L-amino acid formula in resistant dietary protein-induced intestinal disease in infants. J Pediatr. 1997;131(5):658-60. PubMed
    • de Boissieu D, Matarazzo P, Dupont C. Allergy to extensively hydrolyzed cow milk proteins in infants: identification and treatment with an amino acid-based formula. J Pediatr. 1997;131(5):744-7. PubMed
    • Murray ND, Kaufman SS, Vanderhoof JA. Growth of infants with cow milk allergy who were treated with Neocate®. ASPEN 20th Clinical Congress. Jan 14-17, 1996; Washington, DC. 1996;5):397. PubMed
    • Vanderhoof JA, Kaufman SS, Murray MD, et al. Evaluation of Neocate in infants with milk protein induced colitis. NASPGN 1995 Congress. Argentina. J Pediatr Gastroenterol Nutr. 1995;21(3):331(30). Abstract
    • Isolauri E, Sütas Y, Mäkinen-Kiljunen S, et al. Efficacy and safety of hydrolyzed cow milk and amino acid-derived formulas in infants with cow milk allergy. J Pediatr. 1995;127(4):550-7. PubMed
    • Sampson HA, James JM, Bernhisel-Broadbent J. Safety of an amino acid-derived infant formula in children allergic to cow milk. Pediatrics. 1992;90(3):463-5. PubMed
  • Multiple Food Protein Intolerance (MFPI)

    Clinical References for Neocate related to Multiple Food Protein Intolerance (MFPI)

    • Kaczmarski M, Zur E, Kondej-Muszynska K. Therapeutic and nutritional applications of amino acid-based elemental formulas in children with food allergies: a preliminary report. Post Dermatol Alergol. 2012;29(2):86-93.
    • Noimark L, Cox HE. Nutritional problems related to food allergy in childhood. Pediatr Allergy Immunol. 2008;19(2):188-95. PubMed
    • Isolauri E, Sampson HA. Use of an amino acid based formula in the management of cow’s milk allergy and multiple food protein intolerance in children. J Allergy Clin Immunol. 2004;113(2):S154, abstract 518. Abstract
    • Latcham F, Merino F, Lang A, et al. A consistent pattern of minor immunodeficiency and subtle enteropathy in children with multiple food allergy. J Pediatr. 2003;143(1):39-47. PubMed
    • Hill DJ, Heine RG, Cameron DJ, et al. The natural history of intolerance to soy and extensively hydrolyzed formula in infants with multiple food protein intolerance. J Pediatr. 1999;135(1):118-21. PubMed
    • Hill DJ, Cameron DJ, Francis DE, et al. Challenge confirmation of late-onset reactions to extensively hydrolyzed formulas in infants with multiple food protein intolerance. J Allergy Clin Immunol. 1995;96(3):386-94. PubMed
  • Short Bowel Syndrome (SBS)

    Clinical References for Neocate related to Short Bowel Syndrome (SBS)

    • Leechawengwongs E, Tison BE, Gopalakrishna GS, et al. Does short bowel syndrome increase the risk of food allergy and eosinophilic gastrointestinal disease? Observations in Shah-Waardenburg syndrome. J Allergy Clin Immunol. 2013;131(1):251-5. Full Text
    • Woods CW, Ayers K, Turner C, et al. ICAN: Infant Child & Adolescent Nutrition. 2012;5(1):32-6. Abstract
    • Sigalet D, Boctor D, Brindle M, et al. Elements of successful intestinal rehabilitation. J Pediatr Surg. 2011;46(1):150-6. PubMed
    • De Greef E, Mahler T, Janssen A, et al. The influence of Neocate in paediatric short bowel syndrome on PN weaning. J Nutr Metab. 2010;2010. Full Text
    • Theyskens C, Dams A. Enteral nutrition regimen for neonates with short bowel syndrome. Nutrition. 2008;24(10):1045-7. PubMed
    • Hasosah M, Lemberg DA, Skarsgard E, et al. Congenital short bowel syndrome: a case report and review of the literature. Can J Gastroenterol. 2008;22(1):71-4. Full Text
    • Serrano MS, Schmidt-Sommerfeld E. Nutrition support of infants with short bowel syndrome. Nutrition. 2002;18(11-12):966-70. Full Text
    • Andorsky DJ, Lund DP, Lillehei CW, et al. Nutritional and other postoperative management of neonates with short bowel syndrome correlates with clinical outcomes. J Pediatr. 2001;139(1):27-33. PubMed
    • Veereman-Wauters GA, Van Elsacker E, Hoffman I, et al. Successful avoidance of total parenteral nutrition by administration of an amino acid-based enteral formula (Neocate®) in infancy. Digestive Disease Week - 101st Annual AGA Meeting. May 21-4, 2000; San Diego, CA. Gastroenterology. 2000;118(4;Suppl 2:1 of 2):A777(4159). Full Text
    • Brewster D, Kukuruzovic R, Haase A. Short bowel syndrome, intestinal permeability and glutamine. J Pediatr Gastroenterol Nutr. 1998;27(5):614-6. PubMed
    • Bines J, Francis D, Hill D. Reducing parenteral requirement in children with short bowel syndrome: impact of an amino acid-based complete infant formula. J Pediatr Gastroenterol Nutr. 1998;26(2):123-8. PubMed
    • Murray ND, Kaufman SS, Vanderhoof JA. Use of Neocate® in infants with short bowel syndrome. ASPEN 20th Clinical Congress. Jan 14-17, 1996; Washington, DC. 1996;6):397. PubMed
  • Food Protein-Induced Enterocolitis Syndrome (FPIES)

    Clinical References for Neocate related to Food Protein-Induced Enterocolitis Syndrome (FPIES)

    • Mane SK, Bahna SL. Clinical manifestations of food protein-induced enterocolitis syndrome. Curr Opin Allergy Clin Immunol. 2014;14(3):217-21. Full Text
    • Järvinen KM, Nowak-Węgrzyn A. Food protein-induced enterocolitis syndrome (FPIES): current management strategies and review of the literature. J Allergy Clin Immunol Pract. 2013;1(4):317-22.e4. PubMed
    • Anand RK, Appachi E. Case report of methemoglobinemia in two patients with food protein-induced enterocolitis. Clin Pediatr (Phila). 2006;45(7):679-82. PubMed
    • Vanderhoof JA, Murray ND, Kaufman SS, et al. Intolerance to protein hydrolysate infant formulas: an underrecognized cause of gastrointestinal symptoms in infants. J Pediatr. 1997;131(5):741-4. PubMed
    • Kelso JM, Sampson HA. Food protein-induced enterocolitis to casein hydrolysate formulas. J Allergy Clin Immunol. 1993;92(6):909-10. PubMed
  • Atopic Dermatitis

    Clinical References for Neocate related to Atopic Dermatitis

    • Kaczmarski M, Wasilewska J, Lasota M. Hypersensitivity to hydrolyzed cow's milk protein formula in infants and young children with atopic eczema/dermatitis syndrome with cow's milk protein allergy. Rocz Akad Med Bialymst. 2005;50:274-8. PubMed
    • Leung TF, Ma KC, Cheung LT, et al. A randomized, single-blind and crossover study of an amino acid-based milk formula in treating young children with atopic dermatitis. Pediatr Allergy Immunol. 2004;15(6):558-61. PubMed
    • Arvola T, Moilanen E, Vuento R, et al. Weaning to hypoallergenic formula improves gut barrier function in breast-fed infants with atopic eczema. J Pediatr Gastroenterol Nutr. 2004;38(1):92-6. PubMed
    • Isolauri E, Tahvanainen A, Peltola T, et al. Breast-feeding of allergic infants. J Pediatr. 1999;134(1):27-32. PubMed
    • Kuzminskiene R, Vaiciulioniene N. Nutritional management of multiple food protein intolerance induced severe atopic dermatitis in infants. XIX Nordic Congress on Allergology. August 10-13, 1996; Helsinki, Finland. Allergy. 1996;51(Suppl 32):75(P94). Abstract (available for purchase)
    • Isolauri E, Turjanmaa K. Combined skin prick and patch testing enhances identification of food allergy in infants with atopic dermatitis. J Allergy Clin Immunol. 1996;97(1 Pt 1):9-15. PubMed
  • Gastroesophageal Reflux (GER)

    Clinical References for Neocate related to Gastroesophageal Reflux (GER)

    • Borrelli O, Mancini V, Thapar N, et al. Cow's milk challenge increases weakly acidic reflux in children with cow's milk allergy and gastroesophageal reflux disease. J Pediatr. 2012;161(3):476-81 e1. PubMed
    • Thomson M, Wenzl T, Fox A, et al. Effect of an amino acid-based milk - Neocate® - on gastro-oesophageal reflux in infants assessed by combined intraluminal impedance/pH. Pedriatr Asthma Allergy Immunol. 2006;19(4):205-13. Abstract
    • Heine R, Cameron D, Francis D, et al. Effect of amino acid-based formula on gastroesophageal reflux in infants with persistent distress. J Allergy Clin Immunol. 2003;111(2):S102. Abstract
    • Miele E, Staiano A, Tozzi A, et al. Clinical response to amino acid-based formula in neurologically impaired children with refractory esophagitis. J Pediatr Gastroenterol Nutr. 2002;35(3):314-9. PubMed
    • Hill DJ, Heine RG, Cameron DJ, et al. Role of food protein intolerance in infants with persistent distress attributed to reflux esophagitis. J Pediatr. 2000;136(5):641-7. PubMed
    • Miele E, Staiano R, Troncone A, et al. Clinical response to amino acid-based enteral formula in neurologically impaired children with refractory esophagitis. J Pediatr Gastroenterol Nutr. 1999;28(5):561(68). Abstract
    • Hill DJ. Multiple food protein intolerance (MFPI) as a cause of reflux oesophagitis in infancy: results of a pilot study. J Allergy Clin Immunol. 1998;101(1):S89. Missing
    • Hill DJ, Catto-Smith ACS, Cameron DJS, et al. Is multiple food protein intolerance (MFPI) the cause of "reflux oesophagitis" in distressed infants. J Allergy Clin Immunol. 1996;97(1 Pt 3):336-. Abstract
    • Kelly K, Lazenby A, Yardley J, et al. Elemental diet therapy in pediatric patients with chronic reflux symptoms: improvement of esophageal histopathology. Digestive Disease Week - 95th Annual AGA Meeting. May 15-18, 1994; New Orleans, LA. Gastroenterology. 1994;106(4 Suppl 2):A104. PubMed
  • Other Gastrointestinal Conditions

    Clinical References for Neocate related to Other Gastrointestinal Conditions

    • Molnar K, Pinter P, Gyorffy H, et al. Characteristics of allergic colitis in breast-fed infants in the absence of cow's milk allergy. World J Gastroenterol. 2013;19(24):3824-30. Full Text
    • Lee KS, Lee JH. Clinical applications and limitations of a special formula for diarrhea in children. J Korean Med Assoc. 2012;55(6):551-61. Abstract [Full Text in Korean]
    • Drenckpohl D, Vegunta R, Knaub L, et al. Reinfusion of succus entericus into the mucous fistula decreases dependence on parenteral nutrition in neonates. ICAN: Infant Child & Adolescent Nutrition. 2012;4(3):168-74. Abstract
    • de Mattos AP, Ribeiro TC, Mendes PS, et al. Comparison of yogurt, soybean, casein, and amino acid-based diets in children with persistent diarrhea. Nutr Res. 2009;29(7):462-9. PubMed
    • Berni Canani R, Terrin G, Borrelli O, et al. Short- and long-term therapeutic efficacy of nutritional therapy and corticosteroids in paediatric Crohn s disease. Dig Liver Dis. 2006;38(6):381-7. PubMed
    • Amadi B, Mwiya M, Chomba E, et al. Improved nutritional recovery on an elemental diet in Zambian children with persistent diarrhoea and malnutrition. J Trop Pediatr. 2005;51(1):5-10. PubMed
    • Amadi B. Role of food antigen elimination in treating children with persistent diarrhea and malnutrition in Zambia. J Pediatr Gastroenterol Nutr. 2002;34 Suppl 1:S54-6. PubMed
    • Hill DJ, Hosking CS. Infantile colic and food hypersensitivity. J Pediatr Gastroenterol Nutr. 2000;30 Suppl:S67-76. PubMed
    • Estep DC, Kulczycki A, Jr. Colic in breast-milk-fed infants: treatment by temporary substitution of neocate infant formula. Acta Paediatr. 2000;89(7):795-802. PubMed
    • Estep DC, Kulczycki A, Jr. Treatment of infant colic with amino acid-based infant formula: a preliminary study. Acta Paediatr. 2000;89(1):22-7. PubMed
  • Other

    Additional References for Neocate

    • de Groof F, Huang L, van Vliet I, et al. Branched-chain amino acid requirements for enterally fed term neonates in the first month of life. Am J Clin Nutr. 2014;99(1):62-70. PubMed
    • Walker HB. A true case story. Microb Ecol Health Dis. 2012;23. Full Text
    • Seffrood E, Schroth M. Nutrition for orally fed children with spinal muscular atrophy. PNPG Building Block for Life. 2012;35(1):5-8.
    • Raimondi F, Spera AM, Sellitto M, et al. Amino acid-based formula as a rescue strategy in feeding very-low-birth-weight infants with intrauterine growth restriction. J Pediatr Gastroenterol Nutr. 2012;54(5):608-12. PubMed
    • Marcus M. Overview on the principles, implementation, and management of the SMA amino acid diet and common complementary therapies in SMA nutrition. PNPG Building Block for Life. 2012;35(1):15-7.
    • Huang L, Hogewind-Schoonenboom JE, van Dongen MJ, et al. Methionine requirement of the enterally fed term infant in the first month of life in the presence of cysteine. Am J Clin Nutr. 2012;95(5):1048-54. Full Text
    • Huang L, Hogewind-Schoonenboom JE, de Groof F, et al. Lysine requirement of the enterally fed term infant in the first month of life. Am J Clin Nutr. 2011;94(6):1496-503. Full Text
    • Ficicioglu C, Hussa C, Yager C, et al. Effect of galactose free formula on galactose-1-phosphate in two infants with classical galactosemia. Eur J Pediatr. 2008;167(5):595-6. PubMed
    • Torgerson TR, Linane A, Moes N, et al. Severe food allergy as a variant of IPEX syndrome caused by a deletion in a noncoding region of the FOXP3 gene. Gastroenterology. 2007;132(5):1705-17. PubMed
    • Zlatunich CO, Packman S. Galactosaemia: early treatment with an elemental formula. J Inherit Metab Dis. 2005;28(2):163-8. PubMed
    • Heine RG, Cameron DJ, Chow CW, et al. Effect of amino acid-based formula on crying and fussing in infants with persistent distress. J Pediatr Gastroenterol Nutr. 2002;34(4):464(56).
    • Niggemann B, Binder C, Klettke U, et al. In vivo and in vitro studies on the residual allergenicity of partially hydrolysed infant formulae. Acta Paediatr. 1999;88(4):394-8. PubMed
    • Binder C. Therapeutical use of an elemental diet as an infant formula substitution with a dystrophic infant with CF, anus praeter and hypoproteinemia. ICFNG, 4th Dietitians’ Meeting, XXIInd European Cystic Fibrosis Conference. June 13-19, 1998; Berlin, Germany. 1998;76(WN1-5).
    • Isolauri E. Open or blinded challenges in diagnosing food allergy. J Pediatr Gastroenterol Nutr. 1995;20(4):477. Abstract
  • Eosinophilic Esophagitis (EoE) and related Eosinophilic Gastrointestinal Disorders (EGIDs)

    Clinical References for Neocate related to Eosinophilic Esophagitis (EoE) and other Eosinophilic Gastrointestinal Disorders (EGIDs)

    • Rubinstein E, Lee JJ, Fried A, et al. Comparison of two delivery vehicles for viscous budesonide to treat eosinophilic esophagitis in children. J Pediatr Gastroenterol Nutr. 2014;[Epub ahead of print]. PubMed
    • Lucendo AJ, Arias A, Gonzalez-Cervera J, et al. Empiric 6-food elimination diet induced and maintained prolonged remission in patients with adult eosinophilic esophagitis: a prospective study on the food cause of the disease. J Allergy Clin Immunol. 2013;131(3):797-804. Abstract
    • Kalach N, Colson D, Soulaines P, et al. 3-Months elimination diet in childhood EoE: nutritional and immunological aspects. 2013 AAAAI Annual Meeting. February 22-26, 2013; San Antonio, TX. J Allergy Clin Immunol. 2013;131(2):AB181(644). Abstract
    • Hait EJ, Lee J, Fried A, et al. Neocate® Nutra is as effective as sucralose as a delivery vehicle for oral viscous budesonide to treat eosinophilic esophagitis in children. Full Text
    • Groetch M, Nowak-Wegrzyn A. Practical approach to nutrition and dietary intervention in pediatric food allergy. Pediatr Allergy Immunol. 2013;24(3):212-21. PubMed
    • Henderson CJ, Abonia JP, King EC, et al. Comparative dietary therapy effectiveness in remission of pediatric eosinophilic esophagitis. J Allergy Clin Immunol. 2012;129(6):1570-8. PubMed
    • Gorter RR, Heij HA, van der Voorn JP, et al. Eosinophilic esophagitis after esophageal atresia: is there an association? Case presentation and literature review. J Pediatr Surg. 2012;47(6):e9-13. PubMed
    • Haas AM. Development, mealtime dynamics and nutrition: Use of an amino acid-based semi-solid supplement in a child with eosinophilic esophagitis. Clinical Nutrition Week 2011. Vancouver, B.C., Canada. Nutr Clin Pract. 2011;26(1):E19(N36). Abstract
    • Basilious A, Liem J. Nutritional management of eosinophilic gastroenteropathies: case series from the community. Allergy Asthma Clin Immunol. 2011;7:10. Full Text
    • Spergel JM, Brown-Whitehorn TF, Beausoleil JL, et al. 14 years of eosinophilic esophagitis: clinical features and prognosis. J Pediatr Gastroenterol Nutr. 2009;48(1):30-6. PubMed
    • Kagalwalla AF, Sentongo TA, Ritz S, et al. Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis. Clin Gastroenterol Hepatol. 2006;4(9):1097-102. PubMed
    • Chehade M, Magid MS, Mofidi S, et al. Allergic eosinophilic gastroenteritis with protein-losing enteropathy: intestinal pathology, clinical course, and long-term follow-up. J Pediatr Gastroenterol Nutr. 2006;42(5):516-21. PubMed
    • Spergel JM, Andrews T, Brown-Whitehorn TF, et al. Treatment of eosinophilic esophagitis with specific food elimination diet directed by a combination of skin prick and patch tests. Ann Allergy Asthma Immunol. 2005;95(4):336-43. PubMed
    • Liacouras CA, Spergel JM, Ruchelli E, et al. Eosinophilic esophagitis: a 10-year experience in 381 children. Clin Gastroenterol Hepatol. 2005;3(12):1198-206. PubMed
    • Sundaram S, Sunku B, Nelson SP, et al. Adherent white plaques: an endoscopic finding in eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2004;38(2):208-12. PubMed
    • Ko J, Magid MS, Benkov KJ, et al. A 17-month-old boy with periorbital swelling. Ann Allergy Asthma Immunol. 2004;93(3):220-6. PubMed
    • Markowitz JE, Spergel JM, Ruchelli E, et al. Elemental diet is an effective treatment for eosinophilic esophagitis in children and adolescents. Am J Gastroenterol. 2003;98(4):777-82. PubMed
    • Spergel JM, Beausoleil JL, Mascarenhas M, et al. The use of skin prick tests and patch tests to identify causative foods in eosinophilic esophagitis. J Allergy Clin Immunol. 2002;109(2):363-8. PubMed
    • Ruchelli E, Wenner W, Voytek T, et al. Severity of esophageal eosinophilia predicts response to conventional gastroesophageal reflux therapy. Pediatr Dev Pathol. 1999;2(1):15-8. PubMed
    • Kelly KJ, Lazenby AJ, Rowe PC, et al. Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula. Gastroenterology. 1995;109(5):1503-12. PubMed

Educational Courses/Modules

  • NASPGHAN Nutrition University (N2U)

    A specialized nutrition course designed for senior pediatric gastroenterology fellows and junior faculty. This educational activity covers topics related to the practice of pediatric gastroenterology and nutrition and has been proudly supported by Nutricia North America since 2012.