The Nutricia Learning Center features tools and educational resources for Metabolic Healthcare Professionals.

Healthcare Professional Tools


Reference Library

  • XPhe Maxamum®

    Clinical References for XPhe Maxamum®

    • Brown MC, et al Economic impact of feeding a phenylalanine-restricted diet to adults with previously untreated phenylketonuria. J Intell Disabil Res. 1999; 43:30-7. PubMed
    • Cleary MA, et al. Magnetic Resonance Imaging in Phenylketonuria: Reversal of Cerebral White Matter Change. J Pediatr. 1995; 127:251-255. PubMed
    • MacDonald A. Diet and Phenylketonuria: Time for Change? J Hum Nutr Diet. 1994; 7:105-114.
    • Wardley BL & Taitz LS Clinical Trial of a Concentrated Amino Acid Formula for Older Patients with Phenylketouria (XP Maxamum). Eur J Clin Nutr. 1988; 42:81-86.
    • Taitz LS, et al. Zinc and Selenium Levels in Older Children with Phenylketonuria – Correction of Low Plasma Levels by a New Dietary Supplement Formulation (XP Maxamum). Data on file.
  • Periflex LQ (named XPhe Maxamum Drink prior to 2014)

    Clinical References for Periflex LQ (named XPhe Maxamum Drink prior to 2014).

    • Shaw H, Yannicelli S. Acceptability and Clinical use of a new Ready-To-Drink PKU product. Poster presented at annual meeting of GMDI (Genetic Metabolic Dietitians International), Atlanta, USA, 2006.
  • Monogen®

    Clinical References for Monogen®

    • Lessen R. Use of Skim Breast Milk for an Infant with Chylothorax. ICAN (2009); 1 (6):303-10
    • Ficicioglu C, et al. Very long-chain acyl-CoA dehydrogenase deficiency : The effects of accidental fat loading in a a patient detected through newborn screening. J Inherit Metab Dis. 2009 Apr 4 (Epub ahead of print). PubMed
    • Izzard, ME et al. The use of Monogen on the conservative management of chylous fistula. Otolaryng Head Neck. 2007;136 (4 Suppl): S50-3. PubMed
    • Möller A, et al. Congenital intestinal lymphangiectasia: a rare differential diagnosis in hypoproteinemia in infants. Klin Padiatrie. 2006;218(4):224-5 (German). PubMed
    • Cormack, BE et al. Use of Monogen for pediatric postoperative chylothorax. Ann Thorac Surg. 2004; 77(1):301-5. PubMed
    • Ng, PC et al. Deceptive hyperbilirubinaemia in a newborn with familial lipoprotein lipase deficiency. J Paediatr Child H. 2001;37(3):314-6. PubMed
  • Duocal®

    Clinical References for Duocal®

    • Illsinger S, Lücke T, Meyer U, Vaske B, Das AM. Branched chain amino acids as a parameter for catabolism in treated phenylketonuria. Amino Acids. 2005 Feb;28(1):45-50. PubMed
    • Plauth M, Roske AE, Romaniuk P, Roth E, Ziebig R, Lochs H. Post-feeding hyperammonaemia in patients with transjugular intrahepatic portosystemic shunt and liver cirrhosis: role of small intestinal ammonia release and route of nutrient administration. Gut. 2000 Jun;46(6):849-55. PubMed
    • Wilson DC, Cairns P, Halliday HL, Reid M, McClure G, Dodge JA. Randomised controlled trial of an aggressive nutritional regimen in sick very low birthweight infants. Arch Dis Child Fetal Neonatal Ed. 1997 Jul;77(1):F4-11. PubMed
    • Iacona G Carroccio A, Cavataio F & Montalto G. Case report: Multiple food allergy. J Pediatr Gastroenterol Nutr 1993; 16:472-473
    • Morris R, Hart K, Smith V, Shannon L, Bolton J, Abbott R, Alleyne M, Plant H, Slevin ML. A comparison of the energy supplements Polycal and Duocal in cancer patients. J Hum Nutr Diet. 1990; 3: 171-176