Metabolics

 The Nutricia Learning Center features tools and educational resources for Metabolic Healthcare Professionals.

Webinars (CE Eligible)

Nutricia North America is pleased to provide a variety of clinically-oriented educational lectures. These Nutricia sponsored presentations are intended for healthcare professionals.
In this section, you will find the name and description of all the recorded lectures available. Each of the following presentations is approximately 60 minutes long and is available for viewing at no cost. In addition, viewers can receive a certificate of attendance and most lectures are eligible for continuing education credit for dietitians and nurses. In order for the recorded lecture to be considered for continuing education for dietitians by the Commission on Dietetic Registration, the recording must be viewed within 3 years of the date of the live presentation.

  • The Continuing Role of Medical Nutrition in Infants, Teenagers and Adults with Inborn Metabolic Disorders

    Join us for a global, live web event on Wednesday, May 25th, 2022 from 8:00am to 11:00am ET. Chaired by Prof. Dr. Francjan van Spronsen, MD, PhD - Pediatrician Metabolic Diseases, Center of Expertise for PKU and Tyrosinemia, Beatrix Children’s Hospital, University Medical Center of Groningen, The Netherlands.

    *This event is eligible for 2.5 CE credits for dietitians and nurses.

    Find Event Details

    Register for Event

  • Glycomacropeptide for PKU: Sifting Through the Science

    Join us for a 1-hour educational webinar with Sandy van Calcar, PhD, RD, LD for a discussion on the utilization of glycomacropeptide in PKU formulas and a review of the related published research to date.

    Learning Objectives:

    • Explain what glycomacropeptide (GMP) is and how it’s utilized in PKU formulas
    • Summarize the considerations and benefits of GMP for PKU by reviewing the current research
    • Assess how the clinical research findings translate into one’s own clinical practice

    *Nurses may claim CEU credit for this webinar. RDs may claim CEU credit for this webinar until 5/31/2024.


    Download Webinar Handouts

  • Microbiome Dysbiosis: An Emerging Consideration in the Pathophysiology of Inborn Errors of Metabolism

    In this session, recorded for the 2021 Virtual GMDI conference, researcher Trevor Kirby explains gut microbiome dysbiosis and the current understanding of its presence in inborn errors of metabolism (IEMs). Mr. Kirby discusses the gut-brain axis, how dysbiosis might impact disease presentation in IEMs, and the potential role for pre-, pro-, and synbiotics in the therapeutic approach.

    Learning Objectives:

    • Understand dysbiosis and evaluate current research on dysbiosis in IEMs.
    • Define the gut-brain axis and identify how dysbiosis impacts disease presentation.
    • Outline the role pre-, pro-, and synbiotics might play in the therapeutic approach.

    *Nurses may claim CE credit for this webinar. RDs may claim CE credit for this webinar until 4/28/2024. To obtain the code for your certificate of attendance, please fill out this brief survey; then obtain your certificate on NLC.

    Download Webinar Handouts

  • For the love & health of their children: The PKU caregiver study

    Join us for a 1-h educational webinar with Julie Bolduc DeFilippo, MSW, LCSW discussing her research into the experiences of caretakers with PKU from a clinical social worker and PKU mom perspective. She will explain themes that emerged from her research such as diagnosis experience, stages of care and coping strategies as well as provide insight into how healthcare professionals involved in the care of PKU families could improve their clinical practice.

    Participants will be able to:

    • Gain an understanding of the types of need experienced by caregivers of children with PKU
    • Understand any barriers caretakers face
    • Discuss ways, healthcare professionals can better support caretakers of individuals with PKU

    *Nurses may claim CEU credit for this webinar. RDs may claim CEU credit for this webinar until 5/31/2024.


    Download Webinar Handouts

  • Metabolic Formula Requirements in Patients with PKU on BH4: Results and Relevant Recommendations from a Recent Meta-Analysis and US Nutrition Management Guidelines

    Join Dr. Rani Singh for a talk about the important role of metabolic formula intake in the nutritional management of patients with PKU on BH4. Dr. Singh is discussing a recent meta-analysis and its implications on providing guidance for this particular patient population.

    Participants will be able to:

    • Understand the clinical implications of BH4 usage for patients with phenylketonuria (PKU) based on a recent meta-analysis and presenter’s clinical experience
    • Differentiate the nutritional needs of patients on BH4 compared to a classic PKU diet
    • Apply recommendations to one’s own patient population

    *Nurses may claim CE credit for this webinar. RDs may claim CE credit for this webinar from 5/20/2021 to 5/20/2024. To obtain the code for your certificate of attendance, please fill out this brief survey; then obtain your certificate on NLC.

  • Establishing the Microbiome in Early Life: The role of prebiotics in infant nutrition and why it matters in infants with IEMs

    Join us for a one hour educational Webinar with Dr. Kelly Tappenden on the importance of the intestinal microbiome, the role of prebiotics in infant nutrition broadly, and specifically, in infants with inborn errors of metabolism.
    Learning Objectives:

    • Understand the importance of the intestinal microbiome
    • Describe the role of prebiotics in infant nutrition
    • Review how this knowledge applies to infants with inborn errors of metabolism

    *Nurses may claim CE credit for this webinar. RDs may claim CE credit for this webinar from 1/26/2021 to 1/26/2024. To obtain the code for your certificate of attendance, please fill out this brief survey; then obtain your certificate on NLC.

    Download Webinar Handouts

  • Maple Syrup Urine Disease: Pathophysiology, Management, and Outcomes in the Modern Era

    Join us for a one-hour webinar on Maple Syrup Urine Disease (MSUD) with Dr. Kevin Strauss, Medical Director at the Clinic for Special Children (CSC) in Pennsylvania. He will share a retrospective review of MSUD patient outcomes covering 30 years of follow up at CSC, discussing implications for clinical practice and diet management.

    Webinar Objectives:

    • Understand the pathophysiology of MSUD and the rationale behind management with medical food.
    • Identify the components of management that are the primary contributors to good metabolic control in MSUD.
    • Apply learnings to develop nutrition interventions in one’s own clinical setting and practice to contribute to positive outcomes for MSUD patients.

    * Eligible for 1 CE credit for nurses and registered dietitians.

    Download Webinar Handouts

    Download Related Publication

  • Newborn screening follow-up for metabolic disorders during the COVID-19 pandemic: Experiences from the Oregon Metabolic Clinic

    Please join us for a one hour educational webinar with a multi-disciplinary team from Oregan Health & Science University (OHSU) to discuss the implications of COVID-19 on newborn screening procedures. Speakers include: Sarah Viall, PNP, Nurse Practitioner; Leah Wessenberg, RN, MN, FNP-C, Nurse Practitioner; and Joyanna Hansen, PhD, RD, LD, Metabolic Dietitian.

    Webinar Objectives:

    • Recognize the challenges of newborn screening follow-up during a pandemic
    • Discuss alternative ways of working with new families identified through newborn screening
    • Recognize potential for improved patient care opportunities in a post-COVID-19 world

    *Nurses may claim CE credit for this webinar. RDs may claim CE credit for this webinar from 6/17/2020 to 6/17/2023. To obtain the code for your certificate of attendance, please fill out this brief survey; then obtain your certificate on NLC.


    Download Webinar Handouts

  • So, Your Metabolic Patient is an Athlete: Integrating Sports Nutrition Concepts for Patients with Amino Acidopathies

    Please join our speakers, Karen Dolins, EdD, RD, CSSD, CDN and Stephanie Hacker, MS, RD, LDN, CNSC for a free, one-hour educational webinar on sports nutrition for patients with disorders of amino acid metabolism.
    Webinar Objectives:

    • Describe the physiological changes that occur with exercise training and their impact on substrate utilization.
    • Understand nutrition strategies for sports performance.
    • Modify and apply sports nutrition principles for active patients with amino acidopathies, identifying ways to optimize the patient’s metabolic control.

    *This event is eligible for one (1) CE credit. To obtain the code for your certificate of attendance, please fill out this brief survey; then obtain your certificate on NLC.

    Download Webinar Handouts

  • Nutritional Management of Maternal Patients with Inborn Errors of Amino Acid Metabolism: What to Consider

    Please join us for a 1 hour educational webinar with Dr. Sandy van Calcar, Sarah Moran and Manon Bouchard regarding the nutritional management of maternal patients with inborn errors of amino acid metabolism.
    Webinar Objectives:

    • Understand general considerations when managing such patients;
    • Discuss case reports relating to maternal homocystinuria and tyrosinemia;
    • Evaluate application of learnings to one's own clinical practice.

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

    Download Webinar Handouts

  • The What, Why and How of Large Neutral Amino Acids (LNAAs) for Adults with PKU

    Please join Kathryn Moseley, MS, RD, Assistant Professor of Pediatrics at the University of Southern California, Keck School of Medicine, LAC+USC Medical Center in Los Angeles, California.
    By partaking in the webinar, participants will be able to:

    • Understand how LNAAs can be incorporated into PKU management with off-diet individuals, those on standard medical food and those taking sapropterin dihydrochloride
    • Calculate LNAAs and know what to monitor while on LNAAs
    • Hear best practices and case reports with the use of LNAAs

    • *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

    Download Webinar Handouts

  • Part 3: Returning to Diet: Cognitive, affective, and motivational factors for people with PKU

    Join us for a 1 hour educational webinar with Benjamin Goodlett, PhD, Psychology Postdoctoral Fellow at the Metabolism Clinic at Boston Children’s Hospital. He will be exploring mental, motivational and executive functioning barriers that help explain the difficulties many adults with PKU face when returning to diet. Dr. Goodlett will also explain how to help patients overcome these challenges.

    • Understand the cognitive and affective (anxiety & depression) issues associated with adults with PKU when not following a low-PHE diet
    • Discuss the importance of health behavior changes in line with individual’s values
    • Implement strategies to help patients overcome these challenges

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

    Download Webinar Handouts

  • Part 2: Feeding Issues and Formula Transition in Older Children with IEM: Tips from the Experts and How to Overcome Them

    This is part 2 of our 3-part webinar series on feeding and diet topics in inborn errors of metabolism (IEM). Join us for a 1 hour educational webinar with Ligia Brochi, RD, CSP, LDN and Dena Dunn, PsyD (both at Children’s Hospital of Philadelphia) discussing common feeding and formula transition challenges in patients with inborn errors of metabolism.

    Webinar Objectives:

    • Identify possible feeding issue in patients with IEM and know when to refer to a feeding specialist;
    • Describe solutions and tips on how to help overcome formula transition challenges from a RD perspective;
    • Discuss a case report and relate learning to one’s own practice.

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

    Download Webinar Handouts

  • Part 1: Infant and Toddler Feeding in Inborn Errors of Metabolism: A Time of Transition

    This is the first of our 3-part webinar series on feeding and diet topics in inborn errors of metabolism. Please join us and speaker, Amy Cunningham, MS, RD, LDN for a free, 1 hour educational webinar. Amy will be discussing the transition to solids and toddler formula in patients with inborn errors of metabolism (IEM).
    Webinar Objectives:

    • Understand the issues related to introducing solids in patients with IEM.
    • Describe how to best transition young patients with IEM to the next stage formula.
    • Discuss a case report and relate learning to one's own practice.

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

    Download Webinar Handouts

  • The Simplified PKU Diet

    Join our speakers Laurie Bernstein and Fran Rohr in a discussion about the Simplified PKU Diet and how this approach could potentially increase diet adherence and enjoyment of a more normalized approach to food for patients with PKU.
    By partaking in this webinar, participants will be able to:

    • Understand the rationale for using the simplified diet
    • Teach the simplified PKU diet to their patients
    • Share best practices around this approach to PKU management

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • Medical Food and the Brain: What Do We Know?

    Join us for a 1 hour educational webinar with Dr. Kevin Strauss, Medical Director at the Clinic for Special Children, Strasburg, PA, on the topic of brain amino acid metabolism in GA-1 and MSUD.
    At the end of this webinar, participants will be able to: 

    • Understand the relationship between plasma levels and brain uptake of essential amino acids
    • Understand how medical food composition affects brain amino acid nutrition and development in disorders of intermediary metabolism

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • Evolution of Nutricia Products - Milupas & Maxamaids

    As part of our commitment to provide BEST CARE in specialized nutrition, we are continuing to make improvements across our metabolic formulas. Having upgraded our formulas in line with the latest nutritional guidelines, we will no longer supply our line of Maxamaid® and Milupa products starting June 2017 or until supplies last. We recommend you transition your patient to a product within our portfolio that will work for your patients.
    Below are tools that can be found in the Clinician Resources, Metabolics section:

    • Recorded Webinar: Join Ulrike Reichert, Director, Medical and Scientific Affairs - Metabolics/Ketogenics for an informative webinar on the evolution of our Metabolic products and how to successfully transition your patients. Watch Now!
    • Product Transition Tool: Calculation tool to help determine the amount of Nutricia product needed to achieve a desired amount of protein equivalent for individual patients. (Microsoft® Excel files - note, please right click on the link and “Save Target As...” to save this to your desktop and then open through Excel).
    • Nutricia Metabolic Portfolio Guide: Overview of Nutricia's full product portfolio, PKU and Non-PKU disorders.
    • Patient Transition Guide
    Download Webinar Handouts

  • Dietary Management of Tyrosinemia & How to Successfully Transition Your Patients

    Please join our speaker, Manon Bouchard, Dt.P. (CHU Sainte Justine, University of Montréal; Montréal, Canada) as she shares her experiences with the dietary management of tyrosinemia.
    By partaking in this webinar, participants will be able to:

    • Describe the most up-to-date nutritional management for tyrosinemia 
    • Understand key learnings for successful transitions of your patients 
    • Share best practices and case reports


    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • Nutricia Product Series - Monogen: Introducing Our Upgraded Low LCT, High MCT Formula

    Join our speaker, Ulrike Reichert for a free educational webinar on details of our recently launched, upgraded Monogen. Join us to learn more about the latest changes to Nutricia's low LCT, high MCT fomula.
    By attending the webinar, participants will be able to:

    • Describe the key features & benefits of the upgraded Monogen
    • Understand the differences between the previous Monogen vs the upgraded 
    • Access resources for the dietary management of fatty acid oxidation disorders

  • Biochemistry & Management of Fatty Acid Oxidation Disorders: From Infancy to Adulthood

    Please join us for a 1 hour educational webinar with Melanie Gillingham, PhD, RD, Associate Professor; OHSU and Sandy van Calcar, PhD, RD, LD, Assistant Professor; OHSU regarding the biochemical background and management of fatty acid oxidation disorders (emphasis on long chain fatty acid oxidation disorders). 

    Participants will be able to:

    • Understand the biochemical pathways of fatty acid oxidation disorders
    • Describe the nutritional management of the disorders from infancy to adulthood
    • Calculate a diet for this patient group

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

    Download Webinar Handouts

  • Engaging Dietitians in Research and Publications: It's Easier Than a Diet Calculation!

    Please join us for a free, 45-minute educational webinar with Joanna Helm, MS, RD who will share her own research experiences and help you get started on how to write your own research or case study/series for scientific poster publications.

    Participants will be able to

    • Understand how to initiate and participate in scientific research
    • Describe what is needed to successfully publish a paper or poster presentation
    • Formulate a plan for one’s own professional development in publishing

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • Periflex & Anamix Early Years -- Available in CA through MediCal/CCS

    Please join us in learning more about the new Periflex & Anamix Early Years metabolic infant formulas that are now available in CA through MediCal/CCS.  Participants of this webinar will learn about the key features and understand the benefits of the new formulas and understand the nutritional rationale and supporting evidence.  

  • Adrenoleukodystrophy (ALD) and Lorenzo's Oil: An Update

    Join our speaker, Dr. Gerald Raymond, professor of Neurology and Chief of Pediatric Neurology at the University of Minnesota, for an educational webinar on adrenoleukodystrophy and Lorenzo’s Oil.
    By attending the webinar, participants will be able to understand: 

    • Adrenoleukodystrophy: Biochemistry and management 
    • The efficacy of Lorenzo’s Oil 
    • Newborn Screening and Expanded Access: What does this mean for Lorenzo’s Oil? 

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

    Download Webinar Handouts

  • Prebiotics, Microbiome, Infant Nutrition: Beyond the Buzz Words

    Join our speaker, Kelly Tappenden, for an educational webinar on the role of prebiotics for infants with inborn errors of metabolism.  This webinar will cover topics such as microbiome and infant nutrition.  Participants will be able to apply knowledge of prebiotics and gut health when caring for infants with metabolic disorders.
    Dr. Tappenden is a Professor of Nutrition and Gastrointestinal Physiology at the University of Illinois at Urbana-Champaign.  Her work has been focused on individuals with intestinal failure requiring intravenous nutrition and has funded research on the importance of butyrate in relationship to gut health.

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • Prebiotics in Formulas for Infants with Inborn Errors of Metabolism: Experience from the UK

    Join our speaker, Anita MacDonald, Consultant Dietitian in Inherited Metabolic Disorders at Birmingham Children’s Hospital, UK, for an educational webinar on the usage of prebiotics-containing formulas for infants with inborn errors of metabolism.  
    Participants of the webinar will be able to:

    • Identify the available body of evidence and experience in using prebiotic fiber in infants with inborn errors of metabolismUnderstand latest research on the efficacy and acceptability of prebiotics in infants with metabolic disorders
    • Discuss relevant case reports

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • PKU and Bone Health—A Review

    Join us for an educational Webinar with our speaker Steven Yannicelli, PhD, RD; VP for Medical Affairs Nutricia North America, for a review of bone health in PKU.
    By attending the webinar participants will be able to:

    • Understand normal bone metabolism
    • Learn about the published data relating to bone health issues in PKU
    • Draw conclusions for clinical applications

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

    Download Webinar Handouts

  • Nutricia Product Series: DHA and Fiber -- Bringing the best nutritional support to your patients with Inborn Errors of Metabolism

    Join the Nutricia Metabolics Medical Affairs Team (Steven Yannicelli, PhD, RD; Ulrike Reichert, MS; and Linda Leuffgen, RD) for an informational Webinar on the nutritional science behind Nutricia's latest product innovations, including PKU Periflex Junior Plus, PKU Lophlex LQ and Polycal. Participants will be able to 

    • Understand the benefits of DHA, fiber and bone health nutrients
    • Describe the product upgrades to Nutricia’s metabolic product portfolio
    • Identify new tools for their clinical practice.

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • The New PKU Management Guidelines -- Implications for Clinical Practice

    Join us for an educational webinar with metabolic RD experts Amy Cunningham, MS, RD, LDN (Tulane University School of Medicine, LA); Dianne Frazier PhD, RD (consultant); and Laurie Bernstein, MS, RD, FADA (University of Colorado, Denver) to discuss the new Guidelines for the Nutritional Management of PKU.

    Participants will be able to

    • Gain understanding of how the new guidelines were developed.
    • Describe the main recommendations of the new guidelines. 
    • Formulate implications for clinical practice. 

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • Challenges in the Nutritional Management of Maternal IEM Patients

    Join us for an educational Webinar and hear from experts Sandy Van Calcar, PhD, RD and Fran Rohr, Ms, RD, LDN on managing maternal metabolic patients.

    This webinar will cover:

    • Understand the unique nutritional management challenges of maternal IEM patients (non-PKU)
    • Learn about best practices for this patient population
    • Share case reports

    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • Inborn Errors of Metabolism 101: An overview for the non-metabolic healthcare professional

    Join our experts and Dr. J. Charrow and Heather Bausell, RD (both Ann and Robert H. Lurie Children’s Hospital of Chicago) for a one hour presentation on the basics of IEM. This Webinar is a useful resource for all those not working with metabolic patients on a regular basis, but also experienced practitioners training others.

    • A brief overview of NBS
    • What to expect if a metabolic patient presents at the clinic/hospital
    • Overview of dietary management of metabolic patients
    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • Tyrosinemia--Biochemical Background and Advances in Disorder Management

    Join our tyrosinemia experts Dr. Grant Mitchell and Manon Bouchard, Dt. (both CHU Sainte-Justine, Montreal, Canada) for a one hour presentation on background and nutritional management of tyrosinemia.

    This webinar will cover:

    • Understand the biochemical background of tyrosinemia
    • Learn about nutritional management of this patient group
    • Share best practices and case reports
    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • UCD - Background and Advances in Management

    Join our experts in Urea Cycle Disorders Uta Lichter-Konecki, MD, PhD and Erin MacLeod, PhD, RD (Children’s National Medical Center, DC) for a one hour presentation on background and nutritional management of UCDs.

    This webinar will cover:

    • Understand the biochemical background of UCDs
    • Learn about nutritional management of this patient group
    • Share best practices and case reports
    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

  • Demystifying Feeding Challenges

    Please join us for an educational Webinar in our MU Alumni series and hear from feeding experts Dr. Laura Pickler, MD, MPH, and Nancy Creskoff Maune, OTR, about how to recognized and address feeding difficulties in metabolic patients.

    • Anticipate common feeding issues that arise in children with inborn errors of metabolism
    • Be able to initiate strategies to minimize feeding problems when they do arise
    • Protect oral eating potential if enteral nutrition is necessary for medical reasons
    *Please note: Dietitians cannot claim credit for recorded events beyond 3 years from live event date.

Healthcare Professional Tools

Flowcharts/Guidelines

Patient Resources

Case Studies

Reference Library

  • PKU Periflex® Early Years (call Periflex® Infant in Europe)

    Select Clinical References for PKU Periflex Early Years

    • MacDonald A, et al. Specific prebiotics in a formula for infants with phenylketonuria. Mol Genet Metab. 2011;104 Suppl:S55-9. PubMed
  • Periflex® Junior Plus

    Select Clinical References for Periflex Junior Plus

    • Buist NRM, et al. A new amino acid mixture permits new approaches to the treatment of phenylketonuria. Acta Paediatr Suppl. 1994;407:75-7. PubMed
    • Cleary MA, et al. Randomised controlled trial of essential fatty acid supplementation in phenylketonuria. Eur J Clin Nutr. 2006;60(7):915-20. PubMed
  • XPhe Maxamum®

    Select Clinical References for XPhe Maxamum

    • Brown MC, et al Economic impact of feeding a phenylalanine-restricted diet to adults with previously untreated phenylketonuria. J Intell Disabil Res. 1999; 43:30-7. PubMed
    • Cleary MA, et al. Magnetic resonance imaging in phenylketonuria: reversal of cerebral white matter change. J Pediatr. 1995; 127:251-255. PubMed
    • Wardley BL, Taitz LS. Clinical trial of a concentrated amino acid formula for older patients with phenylketouria (Maxamum XP). Eur J Clin Nutr. 1988; 42:81-86. PubMed
  • Phlexy-10®

    Select Clinical References for Phlexy-10

    • MacDonald A, et al. Protein substitutes for PKU: What’s new? J Inherit Metab Dis. 2004; 27:363-371. PubMed
    • Moats RA, et al. Brain phenylalanine concentrations in phenylketonuria: Research and treatment of adults. Pediatrics. 2003;112(6): 1575-9. PubMed
    • Rohr FJ, et al. Acceptability of a new modular protein substitute for the dietary treatment of phenylketonuria. J Inherit Metab Dis. 2001; 24:623-630. PubMed
  • PhenylAde® PheBLOC™ LNAA

    Select Clinical References for PhenylAde PheBLOC LNAA

    • Yano S, et al. Melatonin and dopamine as biomarkers to optimize treatment in phenylketonuria: effects of tryptophan and tyrosine supplementation. J Pediatr. 2014;165:184-9. PubMed
  • GlutarAde™ Junior Drink Mix

    Select Clinical References for GlutarAde Junior Drink Mix

    • Stauss KA, et al. Safety, efficacy and physiological actions of a lysine-free, arginine-rich formula to treat glutaryl-CoA dehydrogenase deficiency: focus on cerebral amino acid influx. Mol Genet Metab. 2011;104(1-2):93-106. PubMed
    • • Strauss, KA et al. Glutaric acidemia type 1: Treatment and outcome of 168 patients over three decades. Mol Genet Metab. 2020;131:325-40. PubMed
  • Complex MSD Products

    Select Clinical References for Complex MSD Products

    • Strauss KA, et al. Classical maple syrup urine disease and brain development: principles of management and formula design. Mol Genet Metab. 2010;99(4):333-45. PubMed
    • Strauss KA, et al. Branched-chain α-ketoacid dehydrogenase deficiency (maple syrup urine disease): Treatment, biomarkers, and outcomes. Mol Genet Metab. 2020;129:193-206. PubMed
  • Monogen®

    Select Clinical References for Monogen

    • Cormack, BE et al. Use of Monogen for pediatric postoperative chylothorax. Ann Thorac Surg. 2004; 77(1):301-5. PubMed
    • Ficicioglu C, et al. Very long-chain acyl-CoA dehydrogenase deficiency: The effects of accidental fat loading in a a patient detected through newborn screening. J Inherit Metab Dis. 2009;32 Suppl 1:S187-90. PubMed
    • Lessen R. Use of Skim Breast Milk for an Infant with Chylothorax. ICAN (2009); 1 (6):303-10. Sage Journals
    • Ng PC, et al. Deceptive hyperbilirubinaemia in a newborn with familial lipoprotein lipase deficiency. J Paediatr Child Health. 2001;37:314-6. PubMed